activated ergosterol - PMC

Thuluz Meza-Menchaca, Angel Ramos-Ligonio, Aracely López-Monteon, Abraham Vidal Limón, Leonid A. Kaluzhskiy, Tatjana V. Shkel, Natallia V. Strushkevich, Luis Felipe Jiménez-García, Lourdes Teresa Agredano Moreno, Verónica Gallegos-García, Jorge Suárez-Medellín, Ángel Trigos

Biomolecules. 2019 Sep; 9(9): 484. Published online 2019 Sep 12. doi: 10.3390/biom9090484

PMCID:: PMC6770379

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A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis

Kristy Koselny, Nebibe Mutlu, Annabel Y. Minard, Anuj Kumar, Damian J. Krysan, Melanie Wellington

mBio. 2018 Jul-Aug; 9(4): e01204-18. Published online 2018 Jul 31. doi: 10.1128/mBio.01204-18

PMCID:: PMC6069111

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Ergosterol Peroxide from the Medicinal Mushroom Ganoderma lucidum Inhibits Differentiation and Lipid Accumulation of 3T3-L1 Adipocytes

Yong-Un Jeong, Young-Jin Park

Int J Mol Sci. 2020 Jan; 21(2): 460. Published online 2020 Jan 10. doi: 10.3390/ijms21020460

PMCID:: PMC7014426

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Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus

Nanbiao Long, Xiaoling Xu, Qiuqiong Zeng, Hong Sang, Ling Lu

Appl Environ Microbiol. 2017 Feb 15; 83(4): e02924-16. Prepublished online 2016 Dec 16. Published online 2017 Feb 1. doi: 10.1128/AEM.02924-16

PMCID:: PMC5288824

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Erg6 affects membrane composition and virulence of the human fungal pathogen Cryptococcus neoformans

Fabiana Freire M. Oliveira, Hugo Costa Paes, Luísa Defranco F. Peconick, Fernanda L. Fonseca, Clara Luna Freitas Marina, Anamélia Lorenzetti Bocca, Mauricio Homem-de-Mello, Márcio Lourenço Rodrigues, Patrícia Albuquerque, André Moraes Nicola, J. Andrew Alspaugh, Maria Sueli S. Felipe, Larissa Fernandes

Fungal Genet Biol. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Fungal Genet Biol. 2020 Jul; 140: 103368. Published online 2020 Mar 19. doi: 10.1016/j.fgb.2020.103368

PMCID:: PMC7293587

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Ergosterol Ameliorates Diabetic Nephropathy by Attenuating Mesangial Cell Proliferation and Extracellular Matrix Deposition via the TGF-β1/Smad2 Signaling Pathway

Zhonghua Dong, Yueyue Sun, Guangwei Wei, Siying Li, Zhongxi Zhao

Nutrients. 2019 Feb; 11(2): 483. Published online 2019 Feb 25. doi: 10.3390/nu11020483

PMCID:: PMC6412245

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Requirement for Ergosterol in Berberine Tolerance Underlies Synergism of Fluconazole and Berberine against Fluconazole-Resistant Candida albicans Isolates

Yi Xu, Hua Quan, Yan Wang, Hua Zhong, Jun Sun, Jianjiang Xu, Nuan Jia, Yuanying Jiang

Front Cell Infect Microbiol. 2017; 7: 491. Published online 2017 Nov 29. doi: 10.3389/fcimb.2017.00491

PMCID:: PMC5712545

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Identification of Candidate Ergosterol-Responsive Proteins Associated with the Plasma Membrane of Arabidopsis thaliana

Thembisile G. Khoza, Ian A. Dubery, Lizelle A. Piater

Int J Mol Sci. 2019 Mar; 20(6): 1302. Published online 2019 Mar 14. doi: 10.3390/ijms20061302

PMCID:: PMC6471938

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The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans

Manjari Shrivastava, Gaëlle S. Kouyoumdjian, Eftyhios Kirbizakis, Daniel Ruiz, Manon Henry, Antony T. Vincent, Adnane Sellam, Malcolm Whiteway

mBio. 2023 Sep-Oct; 14(5): e01807-23. Published online 2023 Oct 4. doi: 10.1128/mbio.01807-23

PMCID:: PMC10653825

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Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2AΔ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis

Tomye L. Ollinger, Bao Vu, Daniel Murante, Josie E. Parker, Lucia Simonicova, Laura Doorley, Mark A. Stamnes, Steven L. Kelly, P. David Rogers, W. Scott Moye-Rowley, Damian J. Krysan

mSphere. 2021 Nov-Dec; 6(6): e00830-21. Published online 2021 Dec 22. doi: 10.1128/msphere.00830-21

PMCID:: PMC8694151

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Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability

Pedro Pais, Raquel Califórnia, Mónica Galocha, Romeu Viana, Mihaela Ola, Mafalda Cavalheiro, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Geraldine Butler, Miguel C. Teixeira

Antimicrob Agents Chemother. 2020 Sep; 64(9): e00554-20. Prepublished online 2020 Jun 22. Published online 2020 Aug 20. doi: 10.1128/AAC.00554-20